• TRSM 2017

  • banner tahniah IDRIS kimia web

  • convo55 web

  • banner kimia 4x10

  • Banner BPRP 2017 2018

  • Web banner

  • slideshow front page 01A

  • Web Banner ICYC 2017 01A

  • PPSKimia Microscale 1

  • PPSKimia Bengkel Peniupan Kaca 1

Announcement @ Chem

 

COURSE ON ELECTROCHEMICAL METHODS FOR CORROSION MONITORING

Date   : 18 - 19 November 2017 (Saturday and Sunday)
Time   : 8:30 am - 5:00 pm
Venue : Conference Room,
School Of Chemical Sciences,USM


  

Viva-voce calon M.sc

Nama Calon : WONG SIEW FANG
Tarikh Viva : 03 November  2017 (JUMAAT)
Masa : 3.00 PM
Tempat : Bilik Mesyuarat,
Pusat Pengajian Sains Kimia


 

Viva-voce calon Ph.D

Nama Calon : Syed Muhammad Al-Amsyar
Tarikh Viva : 01 November 2017 (RABU)
Masa : 2.30 PM
Tempat : Bilik Persidangan,
Pusat Pengajian Sains Kimia


Prof. Dato. Dr. Hasnah Osman

 

 

Contacts:

   (+604)6533576

   (+604)657 4854

     This email address is being protected from spambots. You need JavaScript enabled to view it.



  •  

    header PROFILE

     

    ACADEMIC QUALIFICATIONS

     

     

     ACADEMIC QUALIFICATIONS


    PhD (Organic Chemistry), University of Otago, New Zealand

    B.Sc(Hons) and MSc(Chemistry), USM


     

     

    Biodata

     

     

     

    Biodata

    1. Lecturer for Organic courses

    2. Deputy Dean of Academic, Student Affairs & Alumni)(2016-2018)

    3. Program Manager for The Organic & Inorganic Section (2013-2015)

    4. Program Chairman for Analytical Instruments Laboratory (MUPA) (2010)

    5. Exco member, School of Chemical Sciences (since 2013)

    6. Member of American Chemical Society (since 2009)

    7. Committee Member of Malaysia Natural Products Society (since 2013)

    8. Committee Member of Malaysian Ionic Liquids Research Society (since 2015)

    9. Member of Chemical Institute of Malaysia (IKM)(since 2005)


     

     

     

  •  header RESEARCH

     

    RESEARCH INTEREST

     

    RESEARCH INTEREST

    Organic Synthesis. Natural Products. Green Methods in Organic synthesis. Biological Activities and Drug discovery 


     

     

    RESEARCH TOPICS

     

    RESEARCH TOPICS

    Synthesis And Modification of Selected Natural Products and Its Biological Activities

    Synthetic Study of Angucycline Antibiotic And Its Analogue

    Isolation of Bioactive Compounds From Medicinal Plants

    Multicomponent reactions

    Microwave assisted Organic Reactions

    Ionic Liquids Mediated Organic reactions


     

     

  • header PUBLICATION

     

    SELECTED PUBLICATIONS

     

     SELECTED PUBLICATIONS


    1. Kumar, R. S., Almansour, A.l, Arumugam, N, Menendez, J.C., Osman, H. and kumar, R. R. (2015)
    Dipolar Cycloaddition-Based Multicomponent Reactions in Ionic Liquids: A Green, Fully Stereoselective
    Synthesis of Novel Polycyclic Cage Systems with the Generation of Two New Azaheterocyclic Rings.
    Synthesis,47, 2721-2730.


    2. Ang Chee Wei, Mohamed Ashraf Ali, Yeong Keng Yoon, Sy Bing Choi, Hasnah Osman and Vijay H.
    Masand and Tan Soo Choon (2015) Antimicrobial activity and in silico study of highly functionalized
    dispiropyrrolidines. Medicinal Chemistry Research, 24, 818-828


    3. Elhadi, A.A., Osman, H. Iqbal, M. A., Rajeswari, S. K., Ahamed, M. B. K., Razak, I. A. and Majid, A.S.A
    (2015) Synthesis and structural elucidation of two new series of aurone derivatives as potent inhibitors
    against the proliferation of human cancer cells. Medicinal Chemistry Research, 24(9), 3504-3515


    4. Mohammad, A.T., Yeap, G.-Y, and Osman, H. (2015) Synthesis, characterization and theoretical study
    of a new liquid crystal compound with an oxazepine core. Journal of Molecular structure, 1087, 88-96.


    5. Othman, M.B. H., Akil, H. M., Osman, H., Khan, A. and Ahmad, Z (2015). Synthesis, characterisation
    and thermal properties of hyperbranched polyimide derived from melamine via emulsion polymerization.
    Journal of Thermal Analysis and Calorimetry, 120(3), 1785-1798.


    6. Shahfiza, N, Osman, H, Hock, T. T., Shaari, K. and Abdel-Hamed, A. H. Z. (2015) Metabolomics for
    characterization of gender differences in patients infected with dengue virus, Asian Pacific Journal of
    Tropical Medicine, 8(6), 451-456.


    7. Jamila, N., Khairuddean, Yeong, K. K., Osman, H. and Murugaiyah, V (2015) Cholinesterase inhibitory
    triterpenoids from the bark of Garcinia hombroniana. Journal of Enzyme Inhibition and Medicinal
    Chemistry. 30(1), 133-139


    8. Jamila, N., Yeong, K.K., Murugiah, V.Atlas, A., Khan, I., Khan, N., Khan,S. N., Khairuddean, M and
    Osman, H. (2014) Molecular docking studies and in vitro cholinesterase enzyme inhibitory activities of
    chemical constituents of Garcinia hombroniana. Natural Product Research, 29(1),86-90.


    9. Krishna, S., Reddy, S, Muralikrishna, A, Wan Zuhairi, W. Y., Osman, H. and Varada, R.A. (2014)
    Utilization of the agricultural waste (Cicer arientinum Linn fruit shell biomass) as biosorbent for
    decolorization of Congo red. Desalination and Water Treatment (Article in Press)


    10. Mohammad, A-T., Yeap, G.Y., Osman, H. (2014) Synthesis and mesomorphic behavior of new
    mesogenic compounds possessing a biphenyl ester moiety with a 6-amino-1,3-dimethyluracil, Molecular
    Crystals and Liquid Crystals, 590 (1), 130-139.


    11. Jamila, N., Khairuddean, M., Khan, S.N., Khan, N., Osman, H. (2014) Phytochemicals from the bark of
    Garcinia hombroniana and their biological activities, Records of Natural Products, 8 (3), 312-316


    12. Jamila, N., Khairuddean, M., Yaacob, N.S., Karmal, N.N., Osman, H., Khan S.N., Khan N. (2014)
    Cytotoxic benzophenone and triterpene from Garcinia hombroniana, Bioorganic Chemistry, 54, 60-67.


    13. Kia, Y., Osman, H., Kumar, R.S., Murugaiyah, V., Basiri, A., Khaw, K.Y., Rosil, M.M. (2014) An Efficient
    Ionic Liquid Mediated Synthesis, Cholinesterase Inhibitory Activity and Molecular Modeling Study of
    Novel Piperidone Embedded α ,β-Unsaturated Ketones, Medicinal Chemistry, 10 (5), 512-520.


    14. Mohammad, A-T., Yeap, G.Y., Osman, H. (2014) Synthesis and phase transition studies of new dimer
    compounds connected to a 1,3-dimethylbarbituric acid core, Turkish Journal of Chemistry, 38 (3), 443-
    453.


    15. Kumar, R.S., Almansour, A.I., Arumugam, N., Osman, H., Ali M.A., Basiri A., Kia, Y. (2104) An
    Expedient Synthesis and Screening for Antiacetylcholinesterase Activity of Piperidine Embedded Novel
    Pentacyclic Cage Compounds, Medicinal Chemistry, 10 (2) 228-236.

    16. Yalda Kia, Hasnah Osman, Raju Suresh Kumar, Alireza Basiri, Vikneswaran Murugaiyah, (2014),
    Synthesis and discovery of highly functionalized mono- and bis-spiro-pyrrolidine as potent
    cholinesterase enzyme inhibitors, Bioorganic and Medicinal Chemistry letters, 24(7),1815-1819


    17. Yalda Kia, Hasnah Osman, Raju Suresh Kumar, Vikneswaran Murugaiyah, Alireza Basiri (2014) Ionic
    liquid mediated synthesis of mono- and bis-spirooxindole- hexahydropyrrolidines as cholinesterase
    inhibitors and their molecular docking studies,Bioorganic and Medicinal chemistry, 22 (4), 1318-1328


    18. Asad, M., Beevi, F., ganesan, S. P., Oo, c.-W., Kumar, R. S., Laxmipathi, V, Osman, H., Ali, M. A.
    (2014) Synthesis of novel and highly functionalized 4-hydroxycoumarin chalcone and their pyrazoline
    derivatives as anti-tuberculosis agents. Letters in Drug Design and discovery, 11 (2), 222-230.


    19. Yoon, Y. K., Ali, M. A., Wei, A.C., Choon, T. S., Osman, H, parang, K. Shirazi, A.N. (2014) Synthesis
    and evaluation of novel benzimidazole derivatives as sirtuin inhibitors with antitumor activities.
    Bioorganic and Medicinal chemistry, 22(2), 703-710


    20. Basiri, A, Murugiah, V., Osman, H, Kumar, R. S., Kia, Y, Hooda, A., Parsons, R. B. (2014).
    Cholinesterase inhibitory activity versus aromatic core multiplicity: A facile green synthesis and
    molecular docking study of novel piperidone embedded thiazolopyrimidines. Bioorganic and Medicinal
    chemistry, 22(15), 906-916


    21. Keng Yoon, Y., Ashraf ali, M., Choon, T.S., Ismail, R., Chee wei, A. Suresh Kumar, R, Osman, H.,
    Beevi, F (2013) Antituberculosis: Synthesis and antimycobacterial activity of novel benzimidazole
    derivatives, BioMed research International, 2013, Article No: 926309


    22. Amir, F. Wong, K. C., Eldeen, I, Asmawi, M.Z., Osman, H. (2013), Evaluation of biological activities of
    extracts and chemical constituents of Mimusops elengi, Tropical Journal of Pharmaceutical research, 12
    (4), 591-596


    23. Raja, P.B., Fadaeinasab, M., Qureshi, A.K., Rahim, A.A., Osman, H., Litaudon, M, awing, K. (2013),
    Evaluation of green corrosion Inhibition by alkaloid extracts of Ochrosia oppositifolia and isoreserpiline
    agains mild steel in 1 M HCl medium, Industrial and engineering Chemistry research, 52(31), 10582-
    10593.


    24. Basiri, A., Murugiah, V. osman, H., Kumar, R. S., Kia, Y., Ali, M.A. (2013), Microwave Assisted
    synthesis, cholinesterase enzymes inhibitory activities and molecular docking studies of new
    pyridopyrimidine derivatives, Bioorganic and Medicinal chemistry, 21(11), 3022-3031


    25. Yalda Kia, Hasnah Osman, Raju Suresh Kumar, Vikneswaran Murugaiyah, Alireza Basiri, Subbu
    Perumal, Ibrahim Abdul Razak (2013) A Facile-,region-and Stereoselective Synthesis and
    Cholinesterase Inhibitory Activity of Spirooxindole-pyrrolizine-piperidine hybrids, Bioorganic & Medicinal
    Chemistry Letters,l 2013, (IF 2.54) Elsevier


    26. Yoon, Y.K., Ali, M.A., Wei. A.C., Choon, T.S., Khaw, K.-Y., Murugiah, V., Osman, H., Masand, V. H.
    (2013) Synthesis, characterization, and molecular docking analysis of novel benzimimidazole derivatives
    as cholinesterase inhibitors, Bioorganic chemistry, 49, 33-39.


    27. Basiri, A; Murugaiyah,V; Osman,H; Kumar,R. S; Kia,Y; Awang, K; Ali,M. A (2013) An expedient, ionic
    liquid mediated multi-component synthesis of novel piperidone grafted cholinesterase enzymes
    inhibitors and their molecular modeling study. European Journal of Medical Chemistry, 67, 221-229


    28. Asad, m., Oo, C.-W.,Kumar, R. S., Osman, H, ali, A.A. (2013), Synthesis and Discovery of new
    bisadducts derived from heterocyclic aldehydes and active methylene compounds as potents
    antitubercular agents, Acta Poloniae Pharmaceutica-drug research, 70 (2), 221-228


    29. Abdul Rahim, A. S., Muhamas salhimi, S., Arumugam, N., Pin, L. C., Yee, N. S., Muttiah, N.N., Keat, W.
    B., Abd. Hamid, S. Osman, H., Mat, I. B. (2013), Microwave-assisted Synthesis of sec/tert-butyl-2-
    arylbenzimidazoles and their unexpected antiproliferative activity towards ER negative cancer cells.
    Journal of Enzyme Inhibition and Medicinal chemistry, 28(6), 1255-1260


    30. Al-Mudaris, Z. Z., majid, A.S.A., Ji, D., Al-Mudarris, B.A., Chen, S.-H., Liang, P.-H., Osman, H., Jamal
    Din, S.K.K.K., Abdul Majid, A.M.S. (2013) Conjugation of benzylvanillin and benzamidazole structure
    improves DNA binding with enhanced antileukemic properties, PLoS ONE, 8(11), Article No: e80983


    31. Yalda Kia, Hasnah Osman, Raju Suresh Kumar, Vikneswaran Murugaiyah, Alireza Basiri, Subbu
    Perumal, Habibah A. Wahab, Choi Sy Bing (2013) Synthesis and discovery of novel piperidone-grafted
    mono- and bis-spirooxindole-hexahydropyrrolizines as potent cholinesterase inhibitors, Bioorganic &
    Medicinal Chemistry, Volume 21, Issue 7, 1 April 2013, 1696–1707, (IF 3.16) Elsevier


    32. Pandian Bothi Raja, Ahmad Kaleem Qureshi, Afidah Abdul Rahim, Hasnah Osmana, Khalijah Awang.
    (2013) Neolamarckia cadamba alkaloids as eco-friendly corrosion inhibitors for mild steel in 1M HCl
    media, Corrosion Science, 69 , 292-301, (IF:3.729), Elsevier


    33. Farag, A.M., Guan,T.S., Osman, H. Abdul Majid, A. M. S., Iqbal, M.A., Ahamed,M.B.K. (2013) Synthesis
    of metal(II) [M = Cu, Mn, Zn] Schiff base complexes and their Pro-apoptotic activity in liver tumor cells
    via caspase activation, Medicinal Chemistry Research , 1-10 , Springer


    34. Koay, Y.C., Wong, K.C., Osman, H.,Eldeen, I.M.S., Asmawi, M.Z. (2013), Chemical constituents and
    biological activities of Strobilanthes crispus L, Records of Natural Products 7 (1) , 59-64, (IF:1.508) ,
    Wiley


    35. Pandian Bothi Raja, Ahmad Kaleem Qureshi, Afidah Abdul Rahim, Khalijah Awang, Mat Ropi mukhtar
    and Hasnah Osman. (2013), Indole Alkaloids of Alstonia angustifolia var. latifolia as Green inhibitor for
    Mild Steel Corrosion in 1 M HCl Media.Journal of Materials Engineering and Performance, 22(4), 1072-
    1078. (IF:0.592) Springer


    36. Mohamad Asad, Chuan wei Oo, Raju Suresh Kumar, Hasnah Osman and Mohamed Asraf Ali (2013),
    Synthesis and Discovery of New Bisadducts Derived from Heterocyclic Aldehydes and active Methylene
    Compounds as Potent Antitubercular Agents, acta Poloniac Pharmaceutica-Drug Research, 70(2), 221-
    228, ISSN 0001-6837, Polish Pharmaceutical Society (IF: 0.66) Polskie Towarzystwo Farmaceutyczne


    37. Chuan wei Oo, Hasnah Osman and Sharon Fatinathan and Maizatul Akmar Md Zin (2013), The Uptake
    of copper (II) Ions by Chelating Schiff Base Derived from 4-Aminiantipyrine and 2-
    methoxybenzaldehyde, International Journal of Nonferous Metallurgy, 2, 1-9.


    38.


    39. Al-Douh, M.H., Sahib, H.B., Osman, H., Hamid, S.A., Salhimi, S.M.(2012)Anti-proliferation effects of
    benzimidazole derivatives on HCT-116 colon cancer and MCF-7 breast cancer cell lines,Asian Pacific
    Journal of Cancer Prevention 13 (8), 4075-4079, (IF:0.66) APOCP


    40. Almansour, A.I., Kumar, R.S.,Arumugam, N., Osman, H., Suresh, J.(2012)
    2-Hydroxy-5-[(E)-2-methylbenzylidene]-8-(2-methylphenyl)-9-phenyl-3, 10-
    diazahexacyclo[10.7.1.13,7.02,11.07,11. 016,20]henicosa-1(20),12,14,16,18-pentaen-6-one, Acta
    Crystallographica Section E: Structure Reports Online 68 (12), o3375,(IF: 0.347) Wiley


    41. Abdulrahman I. Almansour, Mohamed Ashraf Ali, Sadath Ali, Ang Chee Wei, Yeong Keng Yoon, Rusli
    Ismail, Tan Soo Choon, Suresh Pandian, Raju Suresh Kumar, Natarajan Arumugam, Hasnah Osman
    (2012). Antimycobacterial Agents: Synthesis and Biological Evaluation of Novel 4-(Substituted-phenyl)-
    6-methyl-2-oxo-N-(pyridin-2-yl)-1,2,3,4-tetrahydropyrimidine- 5-carboxamide Derivatives by Using Onepot
    Multicomponent Method. Letters in Drug Design and Discovery, 9(10), 953-957 (IF:0.805),
    Bentham Science


    42. Noviany Hasan, Hasnah Osman, Suriyati Mohamad, Wong Keng Chong, Khalijah Awang and Anis
    Safirah Mohd Zahariluddin (2012)The Chemical Components of Sesbania grandiflora Root and Their
    Antituberculosis Activity, Pharmaceuticals, 5, 882-889. Taylor and Francis


    43. Ang Chee Wei, Mohamed Ashraf Ali, Yeong Keng Yoon, Rusli Ismail, Tan Soo Choon, Raju Suresh
    Kumar, Natarajan Arumugam, Abdulrahman I. Almansour, Hasnah Osman (2012). Antimycobacterial
    activity: A facile three-component [3+2]-cycloaddition for the regioselective synthesis of highly
    functionalised dispiropyrrolidines. Bioorganic Medicinal Chemistry Leters, 22(15), 4930-4933. (IF:
    2.539), Elsevier


    44. Samina Khan Yusufzai, Hasnah Osman, Aisyah Saad Abdul Rahim, Suhana Arshad and Ibrahim Abdul
    Razak (2012). 3-(2-Methylamino-1,3-thiazol-4-yl)-2Hchromen- 2-one. Acta Cryst. E68(1), o2416-o2417.
    (IF: 0.347), Wiley


    45. Helal, M.H., Al-Mudaris, Z.A., Al-Douh, M.H., Osman, H., Wahab, H.A., Alnajjar, B.O., Abdallah,
    H.H.,Abdul Majid, A.M.S(2012), Diaminobenzene schiff base, a novel class of DNA minor groove binder,
    International Journal of Oncology 41 (2), 504-510, (IF:2.399) Spandidos


    46. Natarajan Arumugam, Aisyah Saad Abdul Rahim, Shafida Abd Hamid and Hasnah Osman
    (2012).Straightforward Synthesis of Novel 1-(2′-α-O-D-Glucopyranosyl ethyl) 2-Arylbenzimidazoles,
    Molecules, 17, 9887-9899. (IF:2.386), MDPI


    47. Kia, Y., Osman, H., Murugaiyah, V.,Arshad, S., Razak, I.A.(2012) (3E,5E)-3,5-Bis(4-methyl-benzyl-idene)-
    1-[3-(piperidin-1-yl)propano-yl] piperidin-4-one, Acta Crystallographica Section E: Structure Reports
    Online 68 (8) , pp. o2493-o2494, (IF: 0.347) Wiley


    48. Faheem Amir, Keng C. Wong, Ibrahim M. Eldeen, Mohammad Z. Asmawi & Hasnah Osman (2012).
    Volatile Constituents and Bioactivities of Mimusops elengi Flowers. Latin American Journal of
    Pharmacy, 31(2), 331-335. (IF:0.288), MedSci


    49. Raju Suresh Kumar, Hasnah Osman, Abdulrahman I. Almansour, Suhana Arshad and Ibrahim Abdul
    Razak (2012). 11-[(E )-2-Fluorobenzylidene]-8-(2-fluorophenyl)-14-hydroxy- 6-thia-3,13-
    diazaheptacyclo- [13.7.1.19,13.02,9.02,14.03,7.019,23]tetracosa- 1(22),15(23),16,18,20-pentaen-10-
    one. Acta Cryst. E68(3), o2094-o2095. (IF: 0.347), Wiley


    50. Kumar, R.S., Osman, H.,Almansour, A.I., Arshad, S., Razak, I.A.(2012)
    11-[(E)-Benzylidene]-14-hydroxy-8-phenyl-6-thia-3,13-diazaheptacyclo-[13.7. 1.19,13.02,9.02,14.03,7.0
    19,23]tetracosa-1(22),15(23),16,18,20-pentaen-10-one, Acta Crystallographica Section E: Structure
    Reports Online 68 (7) , o2013-o2014, (IF:0.347) Wiley


    51. Samina Khan Yusufzai, Hasnah Osman, Habibah A. Wahab, Mohd Mustaqim Rosli and Ibrahim Abdul
    Razak (2012). 2-Cyano-N-[(E)-1-(2-oxo-2H-chromen-3-yl) ethylidene] acetohydrazide Acta Cryst. E68
    (3), o2005. (IF: 0.347), Wiley


    52. Hashim, N.M., Rahim, A.A., Osman, H., Raja, P.B (2012) Quinazolinone compounds as corrosion
    inhibitors for mild steel in sulfuric acid medium, Chemical Engineering Communications 199 (6) , 751-
    766, (IF:0.946) Taylor & Francis


    53. Hasnah Osman, Afsheen Arshad, Chan K Lam, and Mark C Bagley (2012). Microwave-assisted synthesis
    and antioxidant properties of hydrazinyl thiazolyl coumarin derivatives. Chemistry Central Journal,
    6:32.(IF: 3.281), Springer.


    54. Yusufzai, S.K., Osman, H., Abdul Rahim, A.S., Arshad, S., Razak, I.A. (2012)
    3Β-Chloro-6-[2-(2-cyano-acet-yl)hydrazin-1-yl-idene]-5-cholestane, Acta Crystallographica Section E:
    Structure Reports Online 68 (4) , pp. o1056-o1057,(IF:0.347) Wiley.


    55. Abeer Mohamed Farag, Siang Guan Teoh, Hasnah Osman, Madhukar Hemamilini and Hoong-Kun Fun
    (2012). Catena-poly [aquamanganese (III)-μ-(E)-5-bromo-N-[2-(5-bromo-2-oxidobenzyl-ideneamino)-4-
    nitrophenyl]-2-oxido-benzamidato]-N, N-dimethylformamide monosolvate]. Acta Cryst. (2012). E68,
    m365-m366, (IF:0.347), Wiley


    56. Yusufzai, S.K., Osman, H., Rahim, A.S.A., Arshad, S., Razak, I.A. (2012) 3β-Chloro-5-cholestan-6-one,
    Acta Crystallographica Section E: Structure Reports Online 68 (4) , o1211-o1212, (IF: 0.347) Wiley.


    57. Sinha, S., Osman, H., Wahab, H. A. Hemamalini, M. & Fun, H.K. (2012). 4-Methyl-2-oxo-2H-chromen-7-
    yl 4-fluorobenzenesulfonate. Acta Cryst. E68 (3), o641-o642. (IF: 0.347), Wiley


    58. Yalda Kia, Hasnah Osman, Vikneswaran a/l Murugiah, Arshad, S. and Razak, I. A. (2012). (3E,5E)-3,5-
    Bis(naphthalen-1-yl-methyl-idene)piperidin-4-one. Acta Cryst. E68 (3), o802-o803. (IF: 0.347), Wiley


    59. Arumugam, N., Ngah, N., Osman, H., Abdul Rahim A. (2012). Ethyl 1-(2-hydroxyethyl)-2-(4-
    methoxyphenyl)-1H-benzimidazole-5-carboxylate monohydrate. Acta Cryst. E68(3), o421, (IF: 0.347),
    Wiley


    60. Yusufzai, S.K., Osman, H., Sulaiman, O., Arshad, S., Razak, I.A.(2012). 3β-Acetoxy-5α-cholestan-6-one
    2-cyanoacetylhydrazone. Acta Cryst. E68(2), o473-o474. (IF: 0.347), Wiley


    61. Mohamed Ashraf Ali, Rusli Ismail, Tan Soo Choon, Elumalai Manogaran, Raju Suresh Kumar, Hasnah
    Osman, Jeyabalan Govindasamy, Rajesh Yadav, Garima Yadav, Ravinder Kour, Swati Vyas, Hassan,
    Z. and Tneh, S.S.(2012). Synthesis and biological evaluation of novel 6, 7-dimethoxy-3-(4-pyridyl)-2, 3,
    3a, 4-tetrahydroindeno 1, 2-c] pyrazol-2-yl-4- substituted phenylmethanone /ethanone derivatives.
    Journal of Enzyme Inhibition Medicinal Chemistry, 27 (1) , 155-159, (IF:1.617), Informa Healthcare


    62. Yeap, G.-Y., Mohammad, A.-T., Osman, H. (2012). Synthesis and anisotropic properties of novel
    asymmetric diones fused with 1,3-oxazepine and oxazepane rings. Molecular Crystals and Liquid
    Crystals, 552, 177-193, (IF:0.58), Taylor and Francis 


    63. Asad, M., Oo, C.-W. , Osman, H., Fun, H.-K. , Arshad. (2012). 9-(7-Fluoro-4-oxo-4H-chromen-3-yl)-
    3,3,6,6-tetramethyl-2,3,4,5,6,7,8, 9-octahydro-1H-xanthene-1,8-dione, Acta Cryst. E68(1), o38. (IF:
    0.347), Wiley


    64. Mohamed Ashraf Ali, Rusli Ismail, Tan Soo Choon, Raju Suresh Kumar, Hasnah Osman, Natarajan
    Arumugam, Abdulrahman I. Almansour, Karthikeyan Elumalai, Abhimanyu Singh (2012). AChE inhibitor
    : A regio- and stereo-selective 1,3-dipolar cycloaddition for the synthesis of novel substituted 5,6-
    dimethoxy spiro[5.30]-oxindolespiro-[6.300]-2,3-dihydro-1H-inden-100-one-7-(substituted aryl)-
    tetrahydro-1H-pyrrolo[1,2-c][1,3]thiazole. Bioorg. Med. Chem. Lett. 2012, 22,508-511. (IF: 2.539),
    Elsevier


    65. M. R. Islam, S. Muthuraju, C. H. Tarmizi, M. M. Zulkifli, H. Osman, H. Mohamad and J. M. Abdullah
    (2012). Anticonvulsant activity of α-terpineol isolated from Myristica fragrans in GAERS Model of
    Absence Epilepsy, ASM Sci. J., 6(2), 95-102. (IF 0.023), Akademi of Science Malaysia.


    66. Noviany, Hasnah Osman, Wong Keng Chong, Khalijah Awang and Nurhuda Manshoor. (2012) Isolation
    and Characterisation of l, l’-binaphthalene-2,2'-diol, A New Biaryl Natural Product from Sesbania
    grandiflora Root, Int. Journal of Basic & Applied Sciences, 8, 1-4. Science Publishing Coporation


    67. AbdulKarim-TalaqMohammad, Hasnah Osman, Guan-Yeow Yeap (2012). Mechanism study of
    cycloaddition reaction toward the synthesis of 1,3-oxazepane-4,7-diones, Organic chemistry: An Indian
    journal (OCAIJ), 8(2), 41-45. Trade Science Inc.


    68. Aisyah Saad Abdul Rahim, Salizawati Muhamad Salhimi, Natarajan Arumugam, Lim Chung Pin,Ng Shy
    Yee, Nithya Niranjini Muttiah, Wong Boon Keat, Shafida Abd. Hamid, Hasnah Osman,and Ishak b. Mat
    (2012). Microwave-assisted synthesis of sec/tert-butyl 2-arylbenzimidazoles and their unexpected
    antiproliferative activity towards ER negative breast cancer cells. Journal of Enzyme Inhibition and
    Medicinal Chemistry, 1-6. (IF:1.617), Informa Healthcare


    69. Daniel Teoh Chuan Tan, Hasnah Osman, Suriyati and Azlina Harun Kamaruddin, Synthesis and
    Antibacterial Activity of Juglone Derivatives, Journal of Chemistry and Chemical Engineering (JCCE), 6,
    2012, 84-89.David Publishing


    70.

    71. Sinha, S., Osman, H, Wahab, H.A., Hemamalini, M and Fun, HK. (2011). 3-Hydroxy-2-(4
    methoxybenzene-sulfonamido) butanoic acid. Acta Cryst. E67 (12), o3275. (IF: 0.347), Wiley


    72. Arumugam, N., Ngah, N., Osman, H., Abdul Rahim, A.S.(2011) Ethyl 1-(butan-2-yl)-2-(2-methoxyphenyl)-
    1H-benzimidazole-5-carboxylate. E67(12), o3231-o3232. (IF: 0.347), Wiley


    73. Sinha, S., Osman, H, Wahab, H.A., Hemamalini, M and Fun, HK. (2011). 4-Methyl-2-oxo-2H-chromen-7-
    yl 4-methoxybenzenesulfonate. Acta Cryst. E67(12), o3457. (IF: 0.347), Wiley


    74. Kumar, R.S., Osman, H., Kia, Y.,Rosli, M.M., Fun, H.-K. (2011) 5-[(E)-Benzylidene]-2-hydroxy-8,9-
    diphenyl-3,10-diazahexacyclo-[10.7.1. 13,7.02,11.07,11.016,20]henicosa- 1(19),12(20),13,15,17-
    pentaen-6-one, Acta Crystallographica Section E: Structure Reports Online 67 (11) , o2877-o2878,
    (IF:0.347) Wiley


    75. Kumar, R.S., Osman, H., Rahim, A.S.A., Hemamalini, M., Fun, H.-K. (2011) 5-[(E)-4-Fluorobenzylidene]-
    8-(4-fluorophenyl)-2-hydroxy-9-phenyl-3, 10-diazahexacyclo-[10.7.1.13,7.02,11.07,11. 016,20]henicosa-
    1(20),12,14,16,18-pentaen-6-one, Acta Crystallographica Section E: Structure Reports Online 67 (11) ,
    o2879-o2880, (IF:0.347) Wiley


    76. Kumar, R.S., Osman, H., Rahim, A.S.A., Hemamalini, M., Fun, H.-K. (2011) 14-Hydroxy-11-[(E)-4-
    methoxybenzylidene]-8-(4-methoxyphenyl)-5-thia-3, 13-diazaheptacyclo-[13.7.1.19,13.02,9.0
    2,14.03,7.019,23]tetracosa-1(22),15(23),16,18, 20-pentaen-10-one, Acta Crystallographica Section E:
    Structure Reports Online 67 (11) , pp. o2881-o2882, (IF:0.347) Wiley


    77. Afsheen Arshad, Hasnah Osman, Mark C. Bagley, Chan Kit Lam, Suriyati Mohamad and Anis Safirah
    Mohd Zahariluddin (2011). “Synthesis and Antimicrobial Properties of Some New Thiazolyl Coumarin
    Derivatives”, Eur. J. of Med. Chem. 46(9), 3788-3794. (IF:3.346), Elsevier


    78. Raja Pandian Bothi, Rahim Afidah Abdul, Osman Hasnah, Awang Khalijah (2011). Investigation of
    Inhibitive effect of Xylofia ferrungina extract on the corrosion of mild steel in 1 M HCl medium.
    International Journal of Minerals, Metallurgy and Materials, 18(4), 413-418. (IF:0.691), Springer 6


    79. Afsheen Arshad, Hasnah Osman, Chan Kit Lam, madhukar Hemamilini and Hoong-Kun Fun (2011). (E)-
    6-Bromo-3-{2-[2-(2-meth-oxy-benzyl-idene)hydrazine-yl]1,3-thiazol-4yl}-2H-chromen-2-one. Acta
    Cryst(E). E67(7), o1825. (IF: 0.347), Wiley


    80. Asad, M., Oo, C.W., Osman, H., Hemamilini, M & Fun, H.K. (2011). 2-[(E)-(2,4-Dichloro-benzylidene)
    amino]-isoindoline-1,3-dione. Acta Cryst. E67(7), o1712. (IF: 0.347), Wiley


    81. Amira, W. A.W.E., Rahim, A.A., Osman, H., Awang, K., Raja, P.B. (2011). Corrosion Inhibition of Mild
    Steel in 1 M HCL Solution by Xylopia ferruginea leaves from different extract and partition.International
    Journal of Electrochemical science, 6(7),2998-3016.(IF: 3.729), ESG


    82. Raju Suresh Kumar, Mohamed Ashraf Ali, Hasnah Osman, Rusli Ismail, Tan Soo Choon, Yeong Keng
    Yoon, Ang Chee Wei, Suresh Pandian, Elumalai Manogaran. Synthesis and discovery of novel
    hexacyclic cage compounds as inhibitors of acetylcholinesterase. Bioorg. Med. Chem. Lett. 2011,
    21(13),3997-3400, (IF: 2.539), Elsevier


    83. Osman, Hasnah Mohammad, Abdulkarim-Talaq Yeap, Guan-Yeow and Adam, Farook (2011). “Synthesis
    and Characterization of New 3-(3-hydroxyphenyl)-4-alkyl-3,4-dihydrobenzo[e][1,3]oxazepine-1,5-dione
    Compounds”. Chin. J. Chem, 29(7),1518-1522. (IF:0.75), Wiley


    84. Asad, M., Oo, C.W., Osman, H., Rosli, M.M & Fun, H.K. (2011). 3-Hydroxy-2-[(2-hydroxy-4,4-dimethyl-6-
    oxocyclohex-1-en-yl)(thiophen-3-yl)methyl]-5,5-dimethylcyclohex-2-en-1-one. Acta Cryst. E67(7), o1813.
    (IF: 0.347), Wiley


    85. Elyn Amira, W.A.W, Rahim Afidah Abdul, Osman Hasnah, Awang Khalijah (2011). Corrosion inhibition of
    mild steel in 1M HCl solution by Xylofia ferrungina.Research Journal of Chemistry and Environment,
    15(2), 519-529. (IF:0.367)


    86. Basiri, A., Murugiah, V., Osman, H., Hemamalini, M., Fun, H.K (2011). (3E,5E)-1-Acryloyl-3,5-bis(2,4-
    dichloro-benzylidene)piperidin-4-one hemihydrate. Acta Cryst. E67(6), o1301-o1302. (IF: 0.347), Wiley


    87. Yalda Kia, Hasnah Osman, Vikneswaran a/l Murugiah, Madhukar Hemamalini and Hoong-Kun Fun
    (2011). (3E,5E)-3,5-dibenzylidene-1-[3-(piperidin-1-yl)propano-yl]piperidin-4-one. Acta Cryst. E67(6),
    o1299-o1300. (IF: 0.347), Wiley


    88. Rahim, A.A., Saad, B., Osman, H.,Hashim, N., Yahya, S., Talib, K.M. (2011) Simultaneous determination
    of diethylene glycol, diethylene glycol monoethyl ether, coumarin and caffeine in food items by gas
    chromatography, Food Chemistry 126 (3) , 1412-1416, (IF:4.268) Elsevier


    89. Muniandy, M.T., Rahim, A.A.,Osman, H., Shah, A.M., Yahya, S.,Raja, P.B. (2011) Investigation of some
    schiff bases as corrosion inhibitors for aluminium alloy in 0.5 M hydrochloric acid solutions, Surface
    Review and Letters 18 (3-4), 127-133, (IF:0.357) World Scientific


    90. AbdulKarim-Talaq Mohammad, Hasnah Osman and Guan-Yeow Yeap (2011). “Mesamorphic properties
    of heterocyclic 1,3-oxazepane-4,7-diones compounds”. Australian Journal of Basic and Applied
    Sciences, 5(5):551-554. Thomson Reuters


    91. Afsheen Arshad, Hasnah Osman, Chan Kit Lam, madhukar Hemamilini and Hoong-Kun Fun (2011). 6-
    Bromo-3-{2-[2-(diphenylmethylene)hydrazinyl]1,3-thiazol-5-yl}-2H-chromen-2-one chloroform
    monosolvate. Acta Cryst(E). E67(5), o1079-o1080. (IF: 0.347), Wiley


    92. Afsheen Arshad, Hasnah Osman, Chan Kit Lam, madhukar Hemamilini and Hoong-Kun Fun (2011). (E)-
    3-(2-{2-[1-(3-Hydroxyphenyl)ethylidene)hydrazinyl}-1,3-thiazol-4-yl}-2H-chromen-2-one. Acta Cryst(E).
    E67(5), o1072-o1073. (IF: 0.347), Wiley


    93. Basiri, A., Murugiah, V., osman, H., Hemamalini, M., Fun, H.K (2011). (3E,5E)-1-Acryloyl-3,5-bis(2-
    chlorobenzylidene)piperidin-4-one. Acta cryst. E67(5), o1228-o1229. (IF: 0.347), Wiley


    94. Asad, M., Oo, C.W., Osman, H., Rosli, M.M & Fun, H.K. (2011). 4-hydroxy-3-[(4-hydroxy-2-oxo-2H-3-
    chromenyl)(3-thienyl)methyl]-2H-chromen-2-one. Acta Cryst. E67(5), o1037-o1038. (IF: 0.347), Wiley


    95. Raju Suresh Kumar, Hasnah Osman Subbu Perumal, Carlos Menéndez, Mohamed Ashraf Ali, Rusli
    Ismail and Tan Soo Choon(2011). “A facile three-component [3+2]-cycloaddition/annulation domino
    protocol for the regio-, stereo- and product-selective synthesis of novel penta- and hexacyclic cage
    systems, involving the generation of two heterocyclic rings and five contiguous stereocenters”.
    Tetrahedron 67, 3132-3139. (IF:3.06), Elsevier 


    96. AbdulKarim-Talaq Mohammad, Hasnah Osman and Guan-Yeow Yeap (2011). “1,3-Oxazepane-4,7-
    diones compounds. 1H and 13C NMR High-Resolution Spectroscopy (1D and 2D)”. International Journal
    of Spectroscopy, Article ID 945216: Hindawi Pub. Corp.


    97. H.Osman, S.Abd Hamid, M.H.Hussin,L.P.Yee, A.Ab.Rahim, M.H.Al-Douh and S.Yahya(2010).
    Synthesised schiff Bases as a Potential Corrosion Inhibitor of Aluminium. Asian Coordinating Group For
    Chemistry (ACGC), Chem.Res.Comm,24,28-30: ISSN 1020-5586. ACGC


    98. Maidin S. M. M., Idris N., Abdul Majid A. M. S. and Osman H. (2010). “The Potential of Brominated Schiff
    Bases as Antiangiogenesis and anticancer agent”s. Malaysian Journal of pharmaceutical sciences.1,
    185.ISSN 1675-7319. USM


    99. Noviany, Hasnah Osman, Suriyati Mohamad, Wong Keng Chong, Anis safirah Mohd zahariluddin and
    Nabihah Mohd zin (2010). “Antituberculosis flavanoids from the root of Sesbania grandiflora (L)
    Pers.”Malaysian Journal of pharmaceutical sciences.1, 75.ISSN 1675-7319. USM


    100. Helal, M, Al-Douh, M,M Hamid,S. Osman, H., Salhimi, S. & Majid, A. M (2010). Diaminobenzene Schiff
    base Induces Caspase 9-dependent Apoptosis in U937 Leukemia Cells. Webmedcentral.com/article,
    WMC001081, 1-13,ISSN 2046-1690, Hindawi Pub. Corp.


    101. Afidah A. Rahim, Bahruddin Saad, Hasnah Osman, Noorhasani Hashim, Khairuddin Md Talib, Solhan
    Yahya (2010). Simultaneous determination of diethylene glycol, diethylene glycol monoethylether,
    coumarin and caffeine in food items by gas chromatography. Food Chemistry, 126(3), 1412-1416.
    (IF:4.268), Elsevier


    102. Raja Pandian Bothi, Rahim Afidah Abdul, Osman Hasnah, Awang Khalijah (2010). Inhibitory effect of
    Kopsia Singapurensis Extract on the Corrosion Behavior of Mild Steel in Acid Media. Acta Physico
    Chimica Sinica, 26(8), 2171-2176. (IF:0.781), Elsevier


    103. Mohamed Ashraf, Rusli Ismail, Tan Soo Choon, yeong keng Yoon, Ang Chee wei, Suresh Pandian,
    Suressh Kumar, Hasnah Osman and Elumalai Manogaran (2010). Substituted Spiro [2,3'] oxindolespiro
    [3.2"]-5,6-dimethoxy-indane-1"-one-pyrrolidine analogue as inhibitors of acetyl cholinesterase,
    Bioorganic and Medicinal Chemistry Letters 2010, 20, 7064-7066. (IF: 2.539), Elsevier


    104. Adam, F., Hello, K.M., Osman, H. (2010). Synthesis of Mesoporous Silica Immobolized with 3-
    [(Mercapto or amino) propyl] trialkoxysilane by a Simple one-pot Reaction. Chinese Journal of
    Chemistry 28(12), 2383-2388. (IF:0.755), Wiley


    105. Bakhari, N.A., Abdullah, A.R., Osman, H., Nordin, N.H. (2010). The relationship between phenolic,
    tannin and flavanoid content with the antioxidant activity of Pereskia bleo (kunth). CSSR 2010-2010
    International Conference on Science and Social Research, art.no. 5773828, 494-498. WCR


    106. Guan-Yeow Yeap, AbdulKarim-Talaq Mohammad, Hasnah Osman. Synthesis, spectroscopic and
    mesomorphic studies on heterocyclic liquid crystals with 1,3- oxazepine-4,7-dione, 1,3-oxazepane-4,7-
    dione and 1,3-oxazepine-1,5-dione cores. Journal of Molecular Structure, (2010) 982(1-3), 33-44. .
    (IF:1.611), Springer


    107. K. C. Wong, Y. Sivasothy, P. L. Boey ,H. Osman and B. sulaiman.(2010) Essential Oil of Etlingera
    elatior (Jack) R. M. Smith and Etlingeral littoralis (Koenig) Giseke. Journal of Essential Oil Research,
    22(5), 461-466. (IF:0.412), Taylor and Francis


    108. Raja Pandian Bothi, Rahim Afidah Abdul, Osman Hasnah, Awang Khalijah Inhibitory effect of Kopsia
    Singapurensis Extract on the Corrosion Behavior of of Mild Steel in Acid Media, Acta Physico Chimica
    Sinica, (2010), 26(8), 2171-2176. (IF:0.781), Elsevier


    109. Farook Adam, Kasim Mohammed Helo and Hasnah Osman (2010). “The Heterogenation of Melamine
    and its Catalytic Activity”. Applied Catalyst A: General. 382. 115-121, (IF:3.961), Elsevier


    110. Ahmad Makahleh, Bahruddin Saad, Gan Hui Siang, Muhammad Idiris Saleh, Hasnah Osman and
    Baharuddin Salleh. (2010). “Determination of underivatized long chain fatty acids using RP-HPLC with
    capacitively coupled contactless conductivity detection”. Talanta, 81 (2010), 20-24. (IF:3.794), Elsevier


    111. Abeer M. Farag, Siang G. Teoh, Hasnah Osman, Naser E. Eltayeb, Mohamed B. Khadeer Ahamed,
    Amin Malik shah and Ibrahim A.A. Balal (2010), Synthesis, Characterisation and In vitro Cytotoxic
    8 Properties of Some Novel Schiff Base Metal complexes in Hep G2 Cells, World Applied Science Journal, 11 (10), 1196-1209, David Publishing


    112. Farook Adam, Kasim Mohammed Hello and Hasnah Osman (2009). Esterification via saccharine
    mediated silica solid catalyst. Applied Catalysis A: General, 365, 165-172. (IF:3.961), Elsevier


    113. Seok-Keik Tan, Hasnah Osman and Keng-Chong Wong (2009). New phragmalin-type limonoids from
    Swietenia macrophylla King. Food Chemistry, 115 (4), 1279-1285, (IF:4.268), Elsevier


    114. Hasnah Osman, David S Larsen and Jim Simpson. (2009). “Synthesis of an Orthogonally protected DOlivoside,
    1,3-di-O-Acetyl-4-O-benzyl-2,6-dideoxy-D-arabinopyranose, as a C-Glycosyl
    Donor.”Tetrahedron. 65 (21), 4092-4098. , (IF:3.060), Elsevier


    115. Mohammed H. Al-Douh, Hasnah Osman, Shafida A. Hamid (2009). ‘Synthesis, NMR spectroscopy and
    crystal Structures studies of 2-amino-N-(2-hydroxy-3-methoxybenzylidene)analine (2009). ICICI-BME,
    art no, 5417219, IEEE


    116. Hasnah Osman, Afidah A. Rahim, Norhafizah M. Isa And Nornaemah M. Bakhir (2009). “Antioxidants
    Activity and Phenolic Content of Paederia foetida and Syzygium aqueum Extracts”. Molecules. 14, 970-
    978, (IF:2.386), MDPI


    117. Farook Adam, Hasnah Osman and Kasim Mohammed Hello (2009). The Immobilization of 3-
    chloropropyl) triethoxysilane onto silica by a simple one-pot synthesis. Journal of Colloid and Interface
    Science, 331(1), 143-147. (IF:3.263), Elsevier


    118. K. C. Wong, M. S. Tan, D. M. H. Ali, S. G Teoh, H. Osman and S.K. Tan. (2009) “Essential oil of the
    leaves of Sarcandra glabra (Thunb.) Nakai.” Journal of Essential Oil Research. 21, 71-73. (IF: 0.412),
    Taylor and Francis


    119. Seok-Keik Tan, Hasnah Osman and Keng-Chong Wong (2009). Antimicrobial and antioxidant activities
    of Swietenia macrophylla leaf extracts". AJOFAI, 2 (2),ISSN:1906-3040, AFJ


    120. Mohammed H. Al-Douh, Hasnah Osman, Shafida A. Hamid (2009). Indirect Benzylation of Ferulic Acid
    Catalysed by TBAI. Journal of Natural and Applied sciences, 13 (2). SDU


    121. Afidah A. Rahim, Emmanuel Rocca, Jean steinmetz, M. Jain Kassim, M. Sani Ibrahim, Hasnah Osman.
    Antioxidant activities of mangrove Rhizophora apiculata bark extracts. Food Chemistry (2008), 107, 200-
    207. (IF: 4.268), Elsevier

    122. Mohammed Hadi Al-Douh, Shafida Abd Hamid and Hasnah Osman. ‘Efficient Benzylation of O-vanillin
    Using TBAI as Catalyst and The Crystal Structure of the Product’(2008). University of Aden Journal of
    Natural and Applied sciences. University of Aden.


    123. Shazrin S, Hasnah O and Muhammed HA. ‘Synthesis of Ferulic Acid Derivatives’. The Malaysian journal
    of Medical sciences, Volume 15 (1), 2008, 142, USM


    124. Mohammed Hadi Al-Douh, Shafida Abd Hamid and Hasnah Osman. ‘1D and 2D NMR Studies of 2-(2-
    (Benzyloxy)-3-Methoxyphenyl)-1H-Benzimidazole’. Indo. J. Chem. 2007, 7(2), 190-196. Uni. Gadjah
    Mada


    125. I. A. Rahman, J. Ismail and Hasnah Osman. “Studies on Zn (II) Ion Adsorption by Rice Husks Digested
    with Nitric Acid”. Malaysian Journal of Chemistry, 2(1), 012, 2000.


    126. Ismail Ab. Rahman, Jamil Ismail dan Hasnah Osman (1997). “Effect of Nitric Acid Digestion on Organic
    Material and Silica in Rice Husk”. Journal of Materials Chemistry. 7(8), 1505-1509, 1997(IF: 5.97),RSC


     

     

  •  header COLLABORATION

     

     

     

     

  • header OTHER

     

    TEACHING

     

    >

    TEACHING

    KOT 122/4 Organic Chemistry (First Year)

    KUT 206/2 Organic Lab. Course (Second Year)

    KOE 322/3 Natural Products Chemistry (Third Year)

    KOT 323/3 Organic Chemistry (Third Year)

     


     

     

Top

News @ChemUSM

USM ESTABLISHING FURTHER COLLABORATIONS WITH UL FRANCE

USM ESTABLISHING FURTHER COLLABORATIONS WITH UL FRANCE

Program Kimia USM Terima Akreditasi Royal Society Of Chemistry UK.

Program Kimia USM Terima Akreditasi

Penuntut Malaysia Menang Pingat Emas Pertandingan Sains di Parlimen Britain

Penuntut Malaysia Menang  Emas

Global Innovation Challenge

Global Innovation Challenge